Stress is fundamentally defined as force per unit area. Strain is the change in length per unit length. In a Cartesian coordinate system (which we use unless we're doing pipes or spheres), this means that to fully describe the stress and strain in three dimension, we end up with matrices.
Stress is typically written as σ, while strain is ε (we use them for conductivity and dielectric constants too...). By combining our two matrices according to the generalized Hooke's Law
Now we get to the idea of anisotropy, which is the concept that materials don't behave the same in all orientations. For a perfectly isotropic material (like liquid), the strain response will be the same regardless of direction. In this case, the number of independent elastic constants drops to two: Young's modulus and Poisson's ratio. Young's modulus is also known as the modulus of elasticity, while Poisson's ratio describes the degree to which a materials expands in the unconstrained directions when compressed in the third. In an anisotropic material, these values are no longer constants, but instead become matrices as well.
My current research nemesis is the bulk modulus, which is particularly challenging to determine using experiments or simulations. It can either be determined from the derivative of the pressure-volume relationship or the derivative of the pressure-density relationship. In both cases, relaxation and equilibration are critical to minimize scatter in the data. However, reality being what it is, you usually end up with at least some scatter, and can consequently get some crazy derivatives depending on the method you chose for defining the slope at each point.
Bulk modulus is also unique in terms of the anisotropy question: other moduli measure response to a linear stress, be it axial or shear. Bulk modulus describes the compressibility of a material under isotropic pressure, and therefore, the value of the bulk modulus isn't a directional dependent thing. Which is kind of cool. It still makes me want to bang my head on a wall right now, though.